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A STUDY OF LIPID PEROXIDATION INHIBITION OF ENDOPHYTIC FUNGI ISOLATED FROM Kandelia candel DERIVED FROM CAN GIO MANGROVE Tran Thi Minh Dinh * , Nguyen Ngoc Phuong, Nguyen Thi Hang, Duong Thuc Huy Ho Chi Minh City University of Education, Vietnam * Corresponding author: Tran Thi Minh Dinh – Email: firstname.lastname@example.org Received: December 11, 2020; Revised: December 21, 2020; Accepted: December 29, 2020 ABSTRACT Mangrove tree Kandelia candel has been shown to be rich in phenol and flavonoid compounds, resulting in strong antioxidant activity. Therefore, endophytic fungi isolated from this plant can be potentially used to produce antioxidants. In this study, we isolated endophytic fungi from the leaves and roots of K. candel, then investigated basic biological characteristics and the antioxidant activity by reducing power and lipid peroxidation inhibition activity. As a result, four endophytic fungal strains from K. candel leaves and roots were identified and preserved in the Biochemistry and Microbiology Laboratory of the Ho Chi Minh University of Education with the codes of UP-15, UP-16, UP-17, and UP-18. The ethyl acetate extracts from these four strains all show the reducing power. The ethyl acetate extract of the UP-15 strain exhibits the lipid peroxidation inhibition activity with an IC 50 of 396 μg/ml. Keywords:antioxidant activity; Can Gio mangroves; endophytic fungi; Kandelia candel,
lipid peroxidation inhibition