Sơ bộ đánh giá hoạt tính sinh học của một số loài rong và cỏ biển ở Việt Nam
Trần Thị Hồng Hà1, Lê Mai Hương1, Trần Thị Như Hằng1, Nguyễn Đình Luyện1,
Hoàng Kim Chi1, Lê Hữu Cường1, Vũ Đình Giáp1, Đỗ Thị Nhuân1, Đỗ Hữu Nghị1,
Đặng Thị Phương Ly1, Andrey Imbs B.2, Phạm Quốc Long1
1: Viện Hoá học các Hợp chất thiên nhiên, Viện HL Khoa học và Công nghệ Việt Nam
2:Institute of Marine Biology, FEB.
Seaweed and seagrass are considered an underexploited plant resource despite being used in diets and traditional medicine for centuries. Their beneficial properties for human, animals and plants were recognised in the past and are appreciated nowadays. They are of considerable importace as new promising source of a huge number of biologically active compounds. Vietnam is a tropical country and a total number of 350 seaweed species is recorded on the coasts of Vietnam and its numerous islands, showing a rich source of bioactive compounds. In this study, 57 CHCl3/MeOH extracts of seaweed and seagrass samples were tested for bioactivity including antimicrobial, antioxidant and cytotoxic activities. The result showed that 13 extracts (24.07%) had cytotoxicity on 1 cancer cell line and 4 extracts (7.4%) had cytotoxicity on 2 cancer cell lines. For antimicrobial activity, 18 extracts (37.5%) inhibited 1-2 test microbes and 16 extracts (33.33%) inhibited at least 3 test microbes. Of 57 extracts, only 1 extract (1.85%) showed antioxidant activity using DPPH system.
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