Y. TAKAO et al.
E134
25％ of the original frequency; a partial response, from 25% to 50%; a minor response, from 50% to 75%; and
no response, 75% or higher. The therapeutic effect, as based on this classification, was then scored as follows: 3
points
for a complete response, 2 points for a partial response, 1
point for a minor response, 0 points for no
response, and -1 point for a dropout. The scores for each group were calculated and compared.
Analysis of the therapeutic effect of Shakuyaku-kanzo-to for muscle cramps
This part of the analysis evaluated 16 patients, 9 men and 7 women, in the age range 55-80 years (mean age
± SD: 67.94 ± 8.61 years). Patients were administered Shakuyaku-kanzo-to extract granules (No. TJ-68,
Tsumura Co. Ltd., Tokyo, Japan: http://www.tsumura.co.jp/english/products/pi/JPR_T068.pdf) three times daily,
for a total of 7.5 g/day, for 2 weeks.
The patients were asked how many days they needed to obtain the maximum
therapeutic effect and were
classified into four groups: less than 3 days, 3-7 days, 7-14 days, and 14 days or more. We then analyzed the
onset of the therapeutic effect of Shakuyaku-kanzo-to.
Evaluation of adverse drug reactions to Shakuyaku-kanzo-to
The patients were properly informed before treatment about the possible adverse drug reactions of
Shakuyaku-kanzo-to and were instructed to stop taking the Kampo medicine when they experienced any
abnormality. The patients were also instructed to consult a doctor in our pain clinic once every 2
weeks for
measurement of their blood pressure and recording of adverse drug reactions, if any. Routine blood tests were
performed 2 and 12 weeks after the initiation of the medication, or whenever clinically judged necessary.
Chia sẻ với bạn bè của bạn: 
