participants had posterior capsule rupture, which is a
known complication of clear-lens extraction surgery and
is associated with increased risk of poor visual outcomes.
However, the frequency of this complication was low and
was similar to that in large series of cataract surgery.
30
One participant developed malignant glaucoma and
another transient corneal oedema. The net eff ect of these
surgical complications was small because the number of
participants with irreversible loss of vision of more than
ten ETDRS letters was similar in the two treatment
groups; however, the risk of severe complications after
clear-lens extraction must be taken into account from the
perspective of individual patients. The low frequency of
complications associated with clear-lens extraction might
have been related to the skills of the treating surgeons,
who had completed general and specialist training in
ophthalmology and glaucoma, and might not be similar
(n=208)
Laser peripheral
iridotomy (n=211)
Diff erence in change
between groups (95% CI)
p value
(Continued from previous page)
24 months
173, –4·4 (5·3)
172, –5·2 (6·5)
··
··
36 months
172, –4·7 (5·5)
172, –5·0 (6·4)
··
··
Baseline vs 36
months
··
··
0·08 (–0.59 to 0.75)
0·814
Central corneal thickness (μm)*
Baseline
207, 551·5 (37·9)
207, 551·9 (39·2)
··
··
36 months
171, 551·5 (39·6)
164, 543·2 (38·4)
··
··
Refractive error (dioptres)*
Baseline
189, 1·7 (2·3)
191, 1·2 (2·3)
··
··
36 months
168, 0·08 (0·95)
172, 0·92 (2·18)
··
··
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