Safety evaluation of certain food additives
Assessment of dietary exposure
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Assessment of dietary exposure The Committee received an assessment of dietary exposure to cassia gum and additionally accessed data on dietary exposure from the EFSA web site. An EFSA opinion published in 2006 contained an assessment of dietary exposure to cassia gum. Per capita food consumption figures for yogurt and yogurt drinks, ice cream, desserts, processed cream cheese, and canned/preserved meat and poultry items were combined with cassia gum concentrations at the suggested maximum use levels, resulting in an estimated dietary exposure of approximately 195 mg/person per day. Assuming a default body weight of 60 kg, dietary exposure was 3.2 mg/kg bw per day. The EFSA opinion also contained a dietary exposure estimate prepared using individual dietary records for consumers of foods that may contain cassia gum in the USA. Maximum use levels in nine broad food categories were combined with reported food consumption, yielding an estimated mean dietary exposure of 2.1 mg/kg bw per day. Dietary exposure at the 90th percentile was 4.9 mg/kg bw per day. A sponsor supplied an estimate of dietary exposure to cassia gum from its proposed use in four broad food categories: processed cheese at a maximum cassia 24 CASSIA GUM gum level of 3000 mg/kg food; frozen desserts at up to 2500 mg/kg food; and meat products and poultry products at up to 3500 mg/kg food. Food consumption data from the USA (the 2003–2004 NHANES) were used for this analysis. As this survey contains dietary records for 2 non-consecutive days of food consumption, it likely overestimates exposure. To better estimate “usual” consumption, the sponsor proportionally adjusted the 2-day average intakes to 30-day averages using a factor calculated from the number of days on which a food was reported to be consumed over an additional 30-day survey period. The adjusted mean dietary exposure was 2.7 mg/kg bw per day; at the 90th percentile, dietary exposure was 5.4 mg/kg bw per day. The Committee concluded that the estimated 90th-percentile dietary exposure to cassia gum from the proposed uses would be less than 6 mg/kg bw per day. tải về 1.44 Mb. Chia sẻ với bạn bè của bạn:
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