Table of contents 1 Why is particle size important?

RANGE IN MICRONS
0.1-1,000 (1mm)
OPTIMAL APPLICATIONS
POWDERS, SLURRIES,
AND EMULSIONS 
FOOTPRINT
WIDTH 297mm (12”)
DEPTH 420mm (17”) 
HEIGHT 376mm (15”)
RANGE IN MICRONS
0.1-1,000 (1mm)
OPTIMAL APPLICATIONS
POWDERS, SLURRIES,
AND EMULSIONS 
FOOTPRINT
WIDTH 297mm (12”)
DEPTH 420mm (17”) 
HEIGHT 376mm (15”)
The LA-350 Laser Diffraction Particle Size Distribution Analyzer excels in applications as 
diverse as slurries, minerals, and paper chemistry. Based on the advanced optical design 
of previous LA-series analyzers, the LA-350 strikes a harmonious balance between high-
functionality, easy operation, and low maintenance. The optimized design allows for a 
compact optical bench, resulting in an efficient use of bench space, while preserving the
accuracy, precision and resolution that HORIBA’s analyzers are famous for.
SMALL AND POWERFUL
The combination optical bench and circulation pump in one system is one of HORIBA’s 
most popular designs. Now this design has a much smaller footprint which allows the 
analyzer to be moved where it is needed. This is especially valuable for quality control 
situations when the locations of sampling and analysis need to be separate to avoid 
contamination. The optical 
bench and circulation pump 
are combined into a single 
compact system. The compact 
size and low weight make 
this a convenient analyzer for 
today’s crowded laboratories.
LASER 
DIFFRACTION 
TECHNIQUE
Instant automatic alignment function with blanking 
and sample measurement ensures reproducible 
measurements and reliable performances. The laser 
diode light source provides stable performance 
throughout the long lifetime of the analyzer. The 
detectors, lens, and mirrors are protected within 
the interior of the instrument. The design has been 
rigorously tested for durability and robustness.
SIMPLE OPERATION. EXQUISITE PERFORMANCE.
The Partica mini covers a wide range of sizes from 
100nm to 1000 microns. The analysis guarantees 
that production quality and development process will 
be accurate. Measurement accuracy support:±1.4%
guaranteed data accuracy with specified NIST
traceable standard materials.
The Fraction cell optional accessory enables 
measurement of very limited sample amounts and 
collecting them after the measurement. The stir 
bar inside of the cell of the cell prevents the particle 
segregation and sedimentation.
LA-350

RANGE IN MICRONS
10nm - 15µm
OPTIMAL APPLICATIONS 
POWDERS
WEIGHT 27kG (59.5 lbs)
FOOTPRINT
WIDTH 550mm (22”)
DEPTH 660mm (26”) 
HEIGHT 350mm (14”)
A BREAKTHROUGH IN NANOPARTICLE TRACKING ANALYSIS
As with conventional NTA, the instrument visualises scattering from individual 
nanoparticles in suspension. This data is then used to determine particle movement 
and infer particle size using the Stokes Einstein relationship. Then, by using the known 
illuminated and imaged sample volume, particle number concentration is readily 
determined. Thus, from a single measurement, two critical pieces of information are 
determined: particle size distribution and particle concentration.
By incorporating three variable light sources (blue, green and red) the instrument is able 
to select the optimum conditions for any sample analysis, overcoming the limitations of 
NTA when analysing polydisperse sample and enabling a much larger range of particle 
sizes to be visualised.
Furthermore, by introducing the sample in easy-to-use (and clean) cuvette, the 
ViewSizer 3000 is able to repeatedly ‘analyse and stir’, giving a much more reproducible 
result. And because the sample is viewed in a vertical orientation, it is perfect for 
visualising processes such as protein aggregation or crystal dissolution.
HOW IT WORKS
The instrument characterizes nanoparticles by analyzing their thermal-induced motion 
(Brownian motion) and larger, micron-sized particles by analyzing gravitational 
settling. The optical system includes innovative multispectral illumination and detection 
techniques that enable video recording of scattered light from wide-ranging sizes of 
individual particles simultaneously.
The obtained video shows each individual nanoparticle. By taking advantage of modern 
high resolution video cameras and computer graphics processing speed, the motion of 
each particle is tracked to determine the diffusion coefficient, and, from
that, the size of each particle.
A key advancement of this system is 
its ability to work with the very large 
dynamic range of scattered light 
intensity produced by differently-
sized nanoparticles coexisting in a 
polydisperse sample. This technical 
feat is accomplished by combining 
clever software with advanced optics 
and multiple light sources. The 
ViewSizer 3000 technology is an 
elegant and absolute method that 
does not require calibration standards 
or knowledge of particle material 
properties such as refractive index.
NANOTRACKING 
ANALYSIS
ViewSizer
 
3000

The SZ-100 nanoPartica Dynamic Light Scattering (DLS) system 
measures particle size, zeta potential, and molecular weight from 0.3 nm to 8 µm at 
concentrations ranging from 0.1 mg/mL of lysozyme to 40% w/v.
This section explains the underlying principles used by the SZ-100 DLS system.

tải về 7.54 Mb.

Chia sẻ với bạn bè của bạn: