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https://doi.org/10.2174/138955711794519492
A STUDY OF LIPID PEROXIDATION INHIBITION OF ENDOPHYTIC FUNGI
ISOLATED FROM Kandelia candel DERIVED FROM CAN GIO MANGROVE
Tran Thi Minh Dinh
*
, Nguyen Ngoc Phuong, Nguyen Thi Hang, Duong Thuc Huy
Ho Chi Minh City University of Education, Vietnam
*
Corresponding author: Tran Thi Minh Dinh – Email: dinhttm@hcmue.edu.vn
Received: December 11, 2020; Revised: December 21, 2020; Accepted: December 29, 2020
ABSTRACT
Mangrove tree Kandelia candel has been shown to be rich in phenol and flavonoid
compounds, resulting in strong antioxidant activity. Therefore, endophytic fungi isolated from this
plant can be potentially used to produce antioxidants. In this study, we isolated endophytic fungi
from the leaves and roots of K. candel, then investigated basic biological characteristics and the
antioxidant activity by reducing power and lipid peroxidation inhibition activity. As a result, four
endophytic fungal strains from K. candel leaves and roots were identified and preserved in the
Biochemistry and Microbiology Laboratory of the Ho Chi Minh University of Education with the
codes of UP-15, UP-16, UP-17, and UP-18. The ethyl acetate extracts from these four strains all
show the reducing power. The ethyl acetate extract of the UP-15 strain exhibits the lipid
peroxidation inhibition activity with an IC
50
of 396 μg/ml.
Keywords: antioxidant activity; Can Gio mangroves; endophytic fungi; Kandelia candel,
lipid peroxidation inhibition
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